Peroxiredoxin 3 antibody (AA 44-93)

Catalog No. ABIN1453824

The Rabbit Polyclonal anti-Peroxiredoxin 3 antibody (ABIN1453824) specifically detects Peroxiredoxin 3 in WB, IHC, IF, ELISA and IP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Peroxiredoxin 3 antibody (AA 44-93) (ABIN1453824)

Target: Peroxiredoxin 3 (PRDX3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Product Details anti-Peroxiredoxin 3 Antibody

Binding Specificity: AA 44-93

Purpose: PRX III Antibody

Specificity: PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000.IHC:1:50-300 IP 1:50-200 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: PRX III

Background:

Synonyms: PRDX3, AOP1, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog

Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014],

Gene Name: PRDX3

Protein Name: Thioredoxin-dependent peroxide reductase mitochondrial

Molecular Weight: 27 kDa

Gene ID: 10935

OMIM: 604769

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process