SOD1 antibody (AA 36-85)

Catalog No. ABIN1453944

The Rabbit Polyclonal anti-SOD1 antibody (ABIN1453944) specifically detects SOD1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SOD1 antibody (AA 36-85) (ABIN1453944)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOD1 Antibody

Binding Specificity: AA 36-85

Purpose: SOD-1 Antibody

Specificity: SOD-1 Polyclonal Antibody detects endogenous levels of SOD-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SOD-1. AA range:36-85

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD-1

Background:

Synonyms: SOD1, Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],

Gene Name: SOD1

Protein Name: Superoxide dismutase [Cu-Zn]

Molecular Weight: 15 kDa

Gene ID: 6647

OMIM: 147450

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis