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Insulin Receptor antibody (pTyr972)

This anti-Insulin Receptor antibody is a Rabbit Polyclonal antibody detecting Insulin Receptor in WB. Suitable for Human, Mouse and Rat.
Catalog No. ABIN1495716

Quick Overview for Insulin Receptor antibody (pTyr972) (ABIN1495716)

Target

See all Insulin Receptor (INSR) Antibodies
Insulin Receptor (INSR)

Reactivity

  • 175
  • 91
  • 81
  • 16
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  • 8
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  • 6
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  • 4
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  • 2
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Human, Mouse, Rat

Host

  • 164
  • 31
  • 2
  • 1
Rabbit

Clonality

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  • 48
Polyclonal

Conjugate

  • 128
  • 17
  • 15
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  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Insulin Receptor antibody is un-conjugated

Application

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  • 36
  • 25
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  • 15
  • 13
  • 13
  • 9
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 16
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    • 10
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    • 8
    • 8
    • 5
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    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr972

    Specificity

    Human and mouse IR. Rat (100 % homologous) IR has not been tested, but is expected to react. IGF1R [pY950] (75 % homologous) has been shown to cross-react in some cell systems

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ulrich, et al.). The sequence is conserved in mouse and rat.

    Type of Immunogen: Synthetic phospho-peptide
  • Application Notes

    Approved: WB (1:1000)

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Dulbecco's PBS (without Mg2+, Ca2+),  pH 7.3 (+/- 0.1), 50 % glycerol, 1.0 mg/mL BSA (IgG, protease free) as a carrier.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C,-20 °C

    Storage Comment

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target

    Insulin Receptor (INSR)

    Alternative Name

    Insulin Receptor

    Background

    Name/Gene ID: INSR
    Subfamily: Insulin receptor
    Family: Protein Kinase

    Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

    Gene ID

    3643

    UniProt

    P06213

    Pathways

    NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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