Insulin Receptor antibody (pTyr972)
Quick Overview for Insulin Receptor antibody (pTyr972) (ABIN1495716)
Target
See all Insulin Receptor (INSR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr972
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Specificity
- Human and mouse IR. Rat (100 % homologous) IR has not been tested, but is expected to react. IGF1R [pY950] (75 % homologous) has been shown to cross-react in some cell systems
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ulrich, et al.). The sequence is conserved in mouse and rat.
Type of Immunogen: Synthetic phospho-peptide
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Application Notes
- Approved: WB (1:1000)
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Dulbecco's PBS (without Mg2+, Ca2+), pH 7.3 (+/- 0.1), 50 % glycerol, 1.0 mg/mL BSA (IgG, protease free) as a carrier.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Alternative Name
- Insulin Receptor
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Background
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
Gene ID
- 3643
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UniProt
- P06213
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Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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