CBX3 antibody (Middle Region)

Catalog No. ABIN925796

Product Details anti-CBX3 Antibody

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Chicken, Xenopus laevis, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Cow (Bovine), Fruit Fly (Drosophila melanogaster), Frog

Immunogen: CBX3 antibody was raised in rabbit using the middle region of CBX3 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CBX3 Blocking Peptide, catalog no. 33R-2551, is also available for use as a blocking control in assays to test for specificity of this CBX3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Alternative Name: CBX3 (CBX3 Products)

Synonyms: HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane. Synonyms: Polyclonal CBX3 antibody, Anti-CBX3 antibody, chromobox homolog 3, HP1 gamma homolog, Drosophila antibody, HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody.