Bcl-2 antibody (pSer87)
Quick Overview for Bcl-2 antibody (pSer87) (ABIN1531302)
Target
See all Bcl-2 (BCL2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 61-110, pSer87
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Specificity
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BCL-2 (Phospho-Ser87) Antibody detects endogenous levels of BCL-2 only when phosphorylated at Ser87.
PhosphorylationH:S87 M:S84 R:S84
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Ser87.
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Isotype
- IgG
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Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
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Comment
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Unigene-Number: Hs.150749 (NCBI Gene Symbol: BCL2)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable at -20°C for at least 1 year.
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Expiry Date
- 12 months
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Alternative Name
- BCL-2
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Background
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Synonyms: Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, BCL2
NCBI Gene Symbol: BCL2
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Molecular Weight
- 26 kDa
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Gene ID
- 10000
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OMIM
- 151430
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UniProt
- P10415
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Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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