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Bcl-2 antibody (pThr69)

This anti-Bcl-2 antibody is a Rabbit Polyclonal antibody detecting Bcl-2 in IHC, ELISA and IF. Suitable for Human.
Catalog No. ABIN1531491

Quick Overview for Bcl-2 antibody (pThr69) (ABIN1531491)

Target

See all Bcl-2 (BCL2) Antibodies
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Bcl-2 antibody is un-conjugated

Application

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • Binding Specificity

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    AA 46-95, pThr69

    Specificity

    BCL-2 (Phospho-Thr69) Antibody detects endogenous levels of BCL-2 only when phosphorylated at Thr69.

    PhosphorylationH:T69

    Purification

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    Purity

    > 95 %

    Immunogen

    The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Thr69.

    Isotype

    IgG
  • Application Notes

    IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000

    Comment

    Unigene-Number: Hs.150749 (NCBI Gene Symbol: BCL2)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Stable at -20°C for at least 1 year.

    Expiry Date

    12 months
  • Target

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    Alternative Name

    BCL-2

    Background

    Synonyms: Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, BCL2

    NCBI Gene Symbol: BCL2

    Molecular Weight

    26 kDa

    Gene ID

    10000

    OMIM

    151430

    UniProt

    P10415

    Pathways

    MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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