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Caspase 1 antibody (pSer376)

CASP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1531644
  • Target See all Caspase 1 (CASP1) Antibodies
    Caspase 1 (CASP1)
    Binding Specificity
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 342-391, pSer376
    Reactivity
    • 93
    • 34
    • 28
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 103
    • 11
    • 3
    • 1
    Rabbit
    Clonality
    • 94
    • 24
    Polyclonal
    Conjugate
    • 79
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caspase 1 antibody is un-conjugated
    Application
    • 90
    • 46
    • 44
    • 24
    • 14
    • 14
    • 11
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity

    Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.

    PhosphorylationH:S376 M:S374 R:S374

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.
    Isotype
    IgG
    Top Product
    Discover our top product CASP1 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
    Comment

    Unigene-Number: Hs.2490 (NCBI Gene Symbol: CASP1)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    Caspase 1 (CASP1)
    Alternative Name
    Caspase 1 (CASP1 Products)
    Synonyms
    ICE antibody, IL1BC antibody, P45 antibody, Il1bc antibody, Ice antibody, CASP1 antibody, CG5370 antibody, DCP-1 antibody, DCP1 antibody, Dcp1 antibody, Dmel\\CG5370 antibody, ccp1 antibody, dcp-1 antibody, dcp1 antibody, l(2)01862 antibody, l(2)02132 antibody, caspase 1 antibody, caspase 1, apoptosis-related cysteine peptidase antibody, caspase 4, apoptosis-related cysteine peptidase antibody, Death caspase-1 antibody, caspase-1 antibody, caspase antibody, caspase recruitment domain-containing protein 16 antibody, caspase 4 antibody, CASP1 antibody, Casp1 antibody, CASP4 antibody, Dcp-1 antibody, Caspase1 antibody, LOC5564196 antibody, LOC451519 antibody
    Background

    Synonyms: CASP-1, caspase-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

    NCBI Gene Symbol: CASP1

    Molecular Weight
    29 kDa
    Gene ID
    834
    OMIM
    147678
    UniProt
    P29466
    Pathways
    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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