RACGAP1 antibody (pSer387)

Catalog No. ABIN1531650

The Rabbit Polyclonal anti-RACGAP1 antibody (ABIN1531650) specifically detects RACGAP1 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RACGAP1 antibody (pSer387) (ABIN1531650)

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RACGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RACGAP1 Antibody

Binding Specificity: AA 353-402, pSer387

Specificity:

GTPase Activating Protein (Phospho-Ser387) Antibody detects endogenous levels of GTPase Activating Protein only when phosphorylated at Ser387.

PhosphorylationH:S387 M:S388 R:S386

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Ser387.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000

Comment:

Unigene-Number: Hs.505469 (NCBI Gene Symbol: RACGAP1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Alternative Name: GTPase Activating Protein

Background:

Synonyms: GTPase activating protein, GTPase activating protein ID-GAP, MGCRACGAP variant alpha, MGCRACGAP variant beta, RAC GTPase- activating protein 1, RAC GTPase-activating protein, RACGAP1

NCBI Gene Symbol: RACGAP1

Molecular Weight: 71 kDa

Gene ID: 29127

OMIM: 604980

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor