RECQL2 antibody (pSer1141)

Catalog No. ABIN1531762

Product Details anti-RECQL2 Antibody

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Binding Specificity: AA 1107-1156, pSer1141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RECQL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity:

Werner Syndrome Helicase (Phospho-Ser1141) Antibody detects endogenous levels of Werner Syndrome Helicase only when phosphorylated at Ser1141.

PhosphorylationH:S1141

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Werner Syndrome Helicase around the phosphorylation site of Ser1141.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.632050 (NCBI Gene Symbol: WRN)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RECQL2

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Alternative Name: Werner Syndrome Helicase (WRN Products)

Background:

Synonyms: RECQ3, RECQL2, RECQL3, Werner Syndrome helicase

NCBI Gene Symbol: WRN

Molecular Weight: 162 kDa

Gene ID: 7486

OMIM: 114500

UniProt: Q14191

Pathways: DNA Damage Repair