CAMK2B antibody (pThr286)

Catalog No. ABIN1531792

Product Details anti-CAMK2B Antibody

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Binding Specificity: AA 256-305, pThr286

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity:

CaMK2 (Phospho-Thr286) Antibody detects endogenous levels of CaMK2 only when phosphorylated at Thr286.

PhosphorylationH:T286/287 M:T286/287 R:T286/287

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 around the phosphorylation site of Thr286.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.143535, Hs.144114 (NCBI Gene Symbol: CAMK2D)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CaMK2 (CAMK2B Products)

Background:

Synonyms: CAMK2A, CaM-kinase II alpha chain, CaMK-II alpha subunit, CaMKII-alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KCC2A, kinase CaMK2-alpha

NCBI Gene Symbol: CAMK2D

Molecular Weight: 54 kDa

Gene ID: 817

OMIM: 114078

UniProt: Q9UQM7, Q13557

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity