CAMK2B antibody (pThr286)

Catalog No. ABIN1531792

This Rabbit Polyclonal antibody specifically detects CAMK2B in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CAMK2B antibody (pThr286) (ABIN1531792)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CAMK2B Antibody

Binding Specificity: AA 256-305, pThr286

Specificity:

CaMK2 (Phospho-Thr286) Antibody detects endogenous levels of CaMK2 only when phosphorylated at Thr286.

PhosphorylationH:T286/287 M:T286/287 R:T286/287

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 around the phosphorylation site of Thr286.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.143535, Hs.144114 (NCBI Gene Symbol: CAMK2D)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CaMK2

Background:

Synonyms: CAMK2A, CaM-kinase II alpha chain, CaMK-II alpha subunit, CaMKII-alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KCC2A, kinase CaMK2-alpha

NCBI Gene Symbol: CAMK2D

Molecular Weight: 54 kDa

Gene ID: 817

OMIM: 114078

UniProt: Q9UQM7, Q13557

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity