MEF2A antibody (pThr312)

Catalog No. ABIN1531900

This Rabbit Polyclonal antibody specifically detects MEF2A in WB, IHC, IF, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MEF2A antibody (pThr312) (ABIN1531900)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Product Details anti-MEF2A Antibody

Binding Specificity: AA 279-328, pThr312

Purpose: MEF-2 (phospho Thr312) Antibody

Specificity: Phospho-MEF-2 (T312) Polyclonal Antibody detects endogenous levels of MEF-2 protein only when phosphorylated at T312.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Thr312. AA range:279-328

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 μg:mg lysate. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A

Background:

Synonyms: MEF2A, MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Background: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010],

Gene Name: MEF2A

Protein Name: Myocyte-specific enhancer factor 2A

Molecular Weight: 54 kDa

Gene ID: 4205

OMIM: 600660

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades