LCK antibody (pSer59)

Catalog No. ABIN1532092

The Rabbit Polyclonal anti-LCK antibody has been validated for WB and ELISA. It is suitable to detect LCK in samples from Human, Mouse and Rat.

Quick Overview for LCK antibody (pSer59) (ABIN1532092)

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LCK Antibody

Binding Specificity: AA 26-75, pSer59

Specificity:

LCK (Phospho-Ser59) Antibody detects endogenous levels of LCK only when phosphorylated at Ser59.

PhosphorylationH:S59 M:S59 R:S59

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LCK around the phosphorylation site of Ser59.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:40000

Comment:

Unigene-Number: Hs.470627 (NCBI Gene Symbol: LCK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for LCK

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Alternative Name: LCK

Background:

Synonyms: kinase Lck, LCK, LSK, LSK-T, lymphocyte-specific protein tyrosine kinase, P56-LCK, T cell-specific protein-tyrosine kinase

NCBI Gene Symbol: LCK

Molecular Weight: 58 kDa

Gene ID: 3932

OMIM: 153390

UniProt: P06239

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling