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LCK antibody (AA 480-509)

LCK Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031646
  • Target See all LCK Antibodies
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    Binding Specificity
    • 28
    • 16
    • 15
    • 11
    • 10
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 480-509
    Reactivity
    • 167
    • 95
    • 60
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 151
    • 14
    • 2
    Rabbit
    Clonality
    • 146
    • 22
    Polyclonal
    Conjugate
    • 96
    • 10
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This LCK antibody is un-conjugated
    Application
    • 129
    • 87
    • 29
    • 28
    • 24
    • 20
    • 16
    • 14
    • 13
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    Purified
    Immunogen
    A portion of amino acids 480-509 from the human protein was used as the immunogen for this LCK antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LCK Primary Antibody
  • Application Notes
    Titration of the LCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the LCK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    Alternative Name
    LCK (LCK Products)
    Synonyms
    zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody
    Background
    LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
    UniProt
    P06239
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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