FHIT antibody (pTyr114)

Catalog No. ABIN1532181

The Rabbit Polyclonal anti-FHIT antibody is suitable to detect FHIT in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for FHIT antibody (pTyr114) (ABIN1532181)

Target: FHIT (Fragile Histidine Triad (FHIT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHIT antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FHIT Antibody

Binding Specificity: AA 80-129, pTyr114

Specificity:

FHIT (Phospho-Tyr114) Antibody detects endogenous levels of FHIT only when phosphorylated at Tyr114.

PhosphorylationH:Y114

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FHIT around the phosphorylation site of Tyr114.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.655995 (NCBI Gene Symbol: FHIT)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for FHIT

Target: FHIT (Fragile Histidine Triad (FHIT))

Alternative Name: FHIT

Background:

Synonyms: AP3A hydrolase, AP3AASE, Bis(5'-adenosyl)-triphosphatase, Bis(5'-adenosyl)-triphosphatease, Dinucleosidetriphosphatase, Fragile histidine triad protein

NCBI Gene Symbol: FHIT

Molecular Weight: 16 kDa

Gene ID: 2272

OMIM: 144700

UniProt: P49789