SGK1 antibody (AA 41-90)

Catalog No. ABIN1532486

The Rabbit Polyclonal anti-SGK1 antibody (ABIN1532486) specifically detects SGK1 in WB, ELISA, IF, IHC (p) and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SGK1 antibody (AA 41-90) (ABIN1532486)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-SGK1 Antibody

Binding Specificity: AA 41-90

Purpose: SGK1 Antibody

Specificity: SGK1 Polyclonal Antibody detects endogenous levels of SGK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SGK. AA range:41-90

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Alternative Name: SGK

Background:

Synonyms: SGK1, SGK, Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1

Background: SRC proto-oncogene, non-receptor tyrosine kinase(SRC) Homo sapiens This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth.The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: SGK1

Protein Name: Serine/threonine-protein kinase Sgk1

Molecular Weight: 48 kDa

OMIM: 602958

UniProt: O00141

Pathways: MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway