Transferrin Receptor antibody (AA 15-64)

Catalog No. ABIN1532563

There is 1 publication for this product available. The Rabbit Polyclonal anti-Transferrin Receptor antibody is suitable to detect Transferrin Receptor in samples from Human and Mouse. It has been validated for WB, IHC, IF and ELISA.

Quick Overview for Transferrin Receptor antibody (AA 15-64) (ABIN1532563)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-Transferrin Receptor Antibody

Binding Specificity: AA 15-64

Purpose: CD71/TfR Antibody

Specificity: CD71 Polyclonal Antibody detects endogenous levels of CD71 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CD71/TfR. AA range:15-64

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-Transferrin Receptor antibody (ABIN1532563)

Minami, Otsubo, Ieno, Ikeda, Kanazawa, Shimizu, Ohata, Yokochi, Horii, Fukumoto, Taguchi, Takahashi, Oku, Suzuki: "Visualization of sialidase activity in Mammalian tissues and cancer detection with a novel fluorescent sialidase substrate." in: PLoS ONE, Vol. 9, Issue 1, pp. e81941, (2014) (PubMed).

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71/TfR

Background:

Synonyms: TFRC, Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD antigen CD71

Background: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],

Gene Name: TFRC

Protein Name: Transferrin receptor protein 1

Molecular Weight: 84 kDa

Gene ID: 7037

OMIM: 190010

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis