EPHA2/3/4 antibody (AA 556-605)

Catalog No. ABIN1532603

The Rabbit Polyclonal anti-EPHA2/3/4 antibody (ABIN1532603) specifically detects EPHA2/3/4 in WB, IF and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for EPHA2/3/4 antibody (AA 556-605) (ABIN1532603)

Target: EPHA2/3/4 (EPH Receptor A2/3/4 (EPHA2/3/4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPHA2/3/4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-EPHA2/3/4 Antibody

Binding Specificity: AA 556-605

Purpose: EphA2/3/4 Antibody

Specificity: EphA2/3/4 Polyclonal Antibody detects endogenous levels of EphA2/3/4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EPHA2/3/4. AA range:556-605

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPHA2/3/4

Target: EPHA2/3/4 (EPH Receptor A2/3/4 (EPHA2/3/4))

Alternative Name: EPHA2/3/4

Background:

Synonyms: EPHA2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],

Gene Name: EPHA2/3/4

Protein Name: Ephrin type-A receptor 2/3/4

Molecular Weight: 108 kDa

Gene ID: 1969, 2042, 2043

OMIM: 176946

UniProt: P29317