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LAT antibody (AA 86-135)

This Rabbit Polyclonal antibody specifically detects LAT in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN1533125
$341.00
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Quick Overview for LAT antibody (AA 86-135) (ABIN1533125)

Target

See all LAT Antibodies
LAT (Linker For Activation of T Cells (LAT))

Reactivity

  • 155
  • 59
  • 56
  • 1
Human, Mouse, Rat

Host

  • 160
  • 10
  • 2
  • 1
Rabbit

Clonality

  • 140
  • 33
Polyclonal

Conjugate

  • 84
  • 8
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This LAT antibody is un-conjugated

Application

  • 129
  • 57
  • 57
  • 40
  • 40
  • 24
  • 14
  • 13
  • 12
  • 9
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Binding Specificity

    • 20
    • 16
    • 15
    • 13
    • 13
    • 11
    • 10
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 86-135

    Purpose

    LAT Antibody

    Specificity

    LAT Polyclonal Antibody detects endogenous levels of LAT protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Purity

    > 95 %

    Immunogen

    The antiserum was produced against synthesized peptide derived from human LAT. AA range:86-135

    Isotype

    IgG
  • Application Notes

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C/1 year

    Expiry Date

    12 months
  • Target

    LAT (Linker For Activation of T Cells (LAT))

    Alternative Name

    LAT

    Background

    Synonyms: LAT, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38

    Background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: LAT

    Protein Name: Linker for activation of T-cells family member 1

    Molecular Weight

    27 kDa

    Gene ID

    27040

    OMIM

    602354

    UniProt

    O43561

    Pathways

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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