JUP antibody (AA 696-745)

Catalog No. ABIN1533221

This Rabbit Polyclonal antibody specifically detects JUP in WB, IF, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JUP antibody (AA 696-745) (ABIN1533221)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Product Details anti-JUP Antibody

Binding Specificity: AA 696-745

Purpose: Catenin-γ Antibody

Specificity: Catenin-γ Polyclonal Antibody detects endogenous levels of Catenin-γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Catenin-gamma. AA range:696-745

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Catenin-gamma

Background:

Synonyms: JUP, CTNNG, DP3, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3

Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008],

Gene Name: JUP

Protein Name: Junction plakoglobin

Molecular Weight: 81 kDa

Gene ID: 3728

OMIM: 173325

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location