PRKDC antibody (AA 4061-4110)

Catalog No. ABIN1533256

The Rabbit Polyclonal anti-PRKDC antibody (ABIN1533256) specifically detects PRKDC in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for PRKDC antibody (AA 4061-4110) (ABIN1533256)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKDC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PRKDC Antibody

Binding Specificity: AA 4061-4110

Purpose: DNA-PKCS Antibody

Specificity: DNA-PKCS Polyclonal Antibody detects endogenous levels of DNA-PKCS protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DNA-PK. AA range:4061-4110

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: DNA-PK

Background:

Synonyms: PRKDC, HYRC, HYRC1, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460

Background: This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010],

Gene Name: PRKDC

Protein Name: DNA-dependent protein kinase catalytic subunit

Molecular Weight: 469 kDa

Gene ID: 5591

OMIM: 600899

UniProt: P78527

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response