GZMB antibody (AA 10-59)

Catalog No. ABIN1533296

This Rabbit Polyclonal antibody specifically detects GZMB in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GZMB antibody (AA 10-59) (ABIN1533296)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-GZMB Antibody

Binding Specificity: AA 10-59

Specificity:

Granzyme B Antibody detects endogenous levels of total Granzyme B protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Granzyme B.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.1051, Hs.348264 (NCBI Gene Symbol: GZMB)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: Granzyme B

Background:

Synonyms: Granzyme B, Granzyme-2, T-cell serine protease 1-3E, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, SECT, Cathepsin G-like 1, CTSGL1, CTLA-1, Fragmentin-2, Human lymphocyte protein, HLP, C11

NCBI Gene Symbol: GZMB

Molecular Weight: 27 kDa

Gene ID: 2999

OMIM: 123910

UniProt: P10144, P20718

Pathways: Apoptosis, Caspase Cascade in Apoptosis