Vimentin antibody (AA 411-460)
Quick Overview for Vimentin antibody (AA 411-460) (ABIN1533459)
Target
See all Vimentin (VIM) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 411-460
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Purpose
- VIM Antibody
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Specificity
- VIM Polyclonal Antibody detects endogenous levels of VIM protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Vimentin. AA range:411-460
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Isotype
- IgG
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Application Notes
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).
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- Vimentin (VIM)
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Alternative Name
- Vimentin
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Background
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Synonyms: VIM, Vimentin
Background: tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],
Gene Name: VIM
Protein Name: Vimentin
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Molecular Weight
- 53 kDa
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OMIM
- 193060
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UniProt
- P08670
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Pathways
- Caspase Cascade in Apoptosis
Target
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