PERK antibody (AA 61-110)

Catalog No. ABIN1534159

The Rabbit Polyclonal anti-PERK antibody has been validated for WB, ELISA and IF. It is suitable to detect PERK in samples from Human.

Quick Overview for PERK antibody (AA 61-110) (ABIN1534159)

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PERK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-PERK Antibody

Binding Specificity: AA 61-110

Specificity:

E2AK3 Antibody detects endogenous levels of total E2AK3 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human E2AK3.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000

Comment:

Unigene-Number: Hs.591589 (NCBI Gene Symbol: EIF2AK3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PERK

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Background:

Synonyms: E2AK3, EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3 precursor, HsPEK, PEK, PERK, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, kinase PERK

NCBI Gene Symbol: EIF2AK3

Molecular Weight: 125 kDa

Gene ID: 9451

OMIM: 226980

UniProt: Q9NZJ5

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response