Serotonin Receptor 3A antibody (AA 161-210)

Catalog No. ABIN1534245

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 3A in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Serotonin Receptor 3A antibody (AA 161-210) (ABIN1534245)

Target: Serotonin Receptor 3A (HTR3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Serotonin Receptor 3A Antibody

Binding Specificity: AA 161-210

Purpose: SR-3A Antibody

Specificity: SR-3A Polyclonal Antibody detects endogenous levels of SR-3A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human 5-HT-3A. AA range:161-210

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: 5-HT-3A

Background:

Synonyms: HTR3A, 5HT3R, HTR3, 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor

Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily.This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Gene Name: HTR3A

Protein Name: 5-hydroxytryptamine receptor 3A

Molecular Weight: 55 kDa

Gene ID: 3359

OMIM: 182139

UniProt: P46098

Pathways: Synaptic Membrane