GSPT1 antibody (AA 101-150)

Catalog No. ABIN1534414

The Rabbit Polyclonal anti-GSPT1 antibody is suitable to detect GSPT1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC, WB and IF.

Quick Overview for GSPT1 antibody (AA 101-150) (ABIN1534414)

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GSPT1 Antibody

Binding Specificity: AA 101-150

Purpose: eRF3a Antibody

Specificity: ERF3a Polyclonal Antibody detects endogenous levels of eRF3a protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GSPT1. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GSPT1

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Alternative Name: GSPT1

Background:

Synonyms: GSPT1, ERF3A, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 3a, eRF3a, G1 to S phase transition protein 1 homolog

Background: function:Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth.,similarity:Belongs to the GTP-binding elongation factor family. ERF3 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,

Gene Name: GSPT1

Protein Name: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

Molecular Weight: 55 kDa

Gene ID: 2935

OMIM: 139259

UniProt: P15170