MARCH5 antibody (AA 21-70)

Catalog No. ABIN1534863

This Rabbit Polyclonal antibody specifically detects MARCH5 in ELISA, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MARCH5 antibody (AA 21-70) (ABIN1534863)

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MARCH5 Antibody

Binding Specificity: AA 21-70

Purpose: MARCH5 Antibody

Specificity: MARCH5 Polyclonal Antibody detects endogenous levels of 40607 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Alternative Name: MARCH5

Background:

Synonyms: MARCH5, RNF153, E3 ubiquitin-protein ligase MARCH5, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, MARCH-V, Mitochondrial ubiquitin ligase, MITOL, RING finger protein 153

Background: MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],

Gene Name: MARCH5

Protein Name: E3 ubiquitin-protein ligase MARCH5

Molecular Weight: 31 kDa

Gene ID: 54708

OMIM: 610637

UniProt: Q9NX47