NXF3 antibody (AA 72-121)

Catalog No. ABIN1535124

This Rabbit Polyclonal antibody specifically detects NXF3 in ELISA, WB, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NXF3 antibody (AA 72-121) (ABIN1535124)

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXF3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NXF3 Antibody

Binding Specificity: AA 72-121

Purpose: NXF3 Antibody

Specificity: NXF3 Polyclonal Antibody detects endogenous levels of NXF3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NXF3. AA range:72-121

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NXF3

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Alternative Name: NXF3

Background:

Synonyms: NXF3, TAPL3, Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3

Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008],

Gene Name: NXF3

Protein Name: Nuclear RNA export factor 3

Molecular Weight: 60 kDa

Gene ID: 56000

OMIM: 300316

UniProt: Q9H4D5