KCNK4 antibody (AA 332-381)

Catalog No. ABIN1535187

This Rabbit Polyclonal antibody specifically detects KCNK4 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for KCNK4 antibody (AA 332-381) (ABIN1535187)

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNK4 Antibody

Binding Specificity: AA 332-381

Purpose: TRAAK Antibody

Specificity: TRAAK Polyclonal Antibody detects endogenous levels of TRAAK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human KCNK4. AA range:332-381

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Alternative Name: KCNK4

Background:

Synonyms: KCNK4, TRAAK, Potassium channel subfamily K member 4, TWIK-related arachidonic acid-stimulated potassium channel protein, TRAAK, Two pore potassium channel KT4.1, Two pore K(+) channel KT4.1

Background: This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015],

Gene Name: KCNK4

Protein Name: Potassium channel subfamily K member 4

Molecular Weight: 42 kDa

Gene ID: 50801

OMIM: 605720

UniProt: Q9NYG8