RCC2 antibody (AA 473-522)

Catalog No. ABIN1535228

The Rabbit Polyclonal anti-RCC2 antibody (ABIN1535228) specifically detects RCC2 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for RCC2 antibody (AA 473-522) (ABIN1535228)

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RCC2 Antibody

Binding Specificity: AA 473-522

Purpose: RCC2 Antibody

Specificity: RCC2 Polyclonal Antibody detects endogenous levels of RCC2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RCC2

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Alternative Name: RCC2

Background:

Synonyms: RCC2, KIAA1470, TD60, Protein RCC2, RCC1-like protein TD-60, Telophase disk protein of 60 kDa

Background: function:Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subcellular location:Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex.,subunit:Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.,

Gene Name: RCC2

Protein Name: Protein RCC2

Molecular Weight: 56 kDa

Gene ID: 55920

OMIM: 609587

UniProt: Q9P258