RAB11FIP2 antibody (AA 340-389)

Catalog No. ABIN1535246

The Rabbit Polyclonal anti-RAB11FIP2 antibody (ABIN1535246) specifically detects RAB11FIP2 in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for RAB11FIP2 antibody (AA 340-389) (ABIN1535246)

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB11FIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RAB11FIP2 Antibody

Binding Specificity: AA 340-389

Purpose: Rab11-FIP2 Antibody

Specificity: Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RAB11FIP2

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Alternative Name: RAB11FIP2

Background:

Synonyms: RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11

Background: function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,

Gene Name: RAB11FIP2

Protein Name: Rab11 family-interacting protein 2

Molecular Weight: 58 kDa

Gene ID: 22841

OMIM: 608599

UniProt: Q7L804

Pathways: Hormone Transport, Carbohydrate Homeostasis