PLK3 antibody (AA 231-280)

Catalog No. ABIN1535338

The Rabbit Polyclonal anti-PLK3 antibody is suitable to detect PLK3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PLK3 antibody (AA 231-280) (ABIN1535338)

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLK3 Antibody

Binding Specificity: AA 231-280

Purpose: Fnk Antibody

Specificity: Fnk Polyclonal Antibody detects endogenous levels of Fnk protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PLK3. AA range:231-280

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLK3

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Alternative Name: PLK3

Background:

Synonyms: PLK3, CNK, FNK, PRK, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/threonine-protein kinase, FGF-inducible kinase, Polo-like kinase 3, PLK-3, Proliferation-related kinase

Background: The protein encoded byThis gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015],

Gene Name: PLK3

Protein Name: Serine/threonine-protein kinase PLK3

Molecular Weight: 71 kDa

Gene ID: 1263

OMIM: 602913

UniProt: Q9H4B4

Pathways: Regulation of long-term Neuronal Synaptic Plasticity