Histone H2B antibody (H2BK12ac)

Catalog No. ABIN1535516

The Rabbit Polyclonal anti-Histone H2B antibody (ABIN1535516) specifically detects Histone H2B in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for Histone H2B antibody (H2BK12ac) (ABIN1535516)

Target: Histone H2B

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Histone H2B Antibody

Binding Specificity: AA 10-59, H2BK12ac

Purpose: Acetyl Histone H2B (K12) Antibody

Specificity: Acetyl-Histone H2B (K12) Polyclonal Antibody detects endogenous levels of Histone H2B protein only when acetylated at K12.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H2B around the acetylated site of Lys12. AA range:10-59

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Histone H2B

Target: Histone H2B

Background:

Synonyms: H2BFS, Histone H2B type F-S, Histone H2B.s, H2B/s

Background: H2BFS (H2B Histone Family Member S (Pseudogene)) is a Pseudogene. Diseases associated with H2BFS include endometrial stromal sarcoma. Among its related pathways are Packaging Of Telomere Ends. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BH.

Gene Name: H2BFS

Protein Name: Histone H2B type F-S

Molecular Weight: 13 kDa

Gene ID: 54145

UniProt: P57053