GLP1R antibody (AA 101-150)

Catalog No. ABIN1535693

The Rabbit Polyclonal anti-GLP1R antibody (ABIN1535693) specifically detects GLP1R in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLP1R antibody (AA 101-150) (ABIN1535693)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLP1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GLP1R Antibody

Binding Specificity: AA 101-150

Purpose: GLP-1R Antibody

Specificity: GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Alternative Name: GLP1R

Background:

Synonyms: GLP1R, Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R

Background: glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

Gene Name: GLP1R

Protein Name: Glucagon-like peptide 1 receptor

Molecular Weight: 53 kDa

Gene ID: 2740

OMIM: 138032

UniProt: P43220

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour