Lamin A/C antibody (Cleaved-Asp230)

Catalog No. ABIN1536092

This anti-Lamin A/C antibody is a Rabbit Polyclonal antibody detecting Lamin A/C in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Lamin A/C antibody (Cleaved-Asp230) (ABIN1536092)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Lamin A/C Antibody

Binding Specificity: AA 181-230, Cleaved-Asp230

Specificity:

Lamin A (Cleaved-Asp230) Antibody detects endogenous levels of fragment of activated Lamin A resulting from cleavage adjacent to Asp230.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Lamin A.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.594444 (NCBI Gene Symbol: LMNA)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: Lamin A

Background:

Synonyms: 70 kDa lamin, LAMA, LMN1, LMNA

NCBI Gene Symbol: LMNA

Molecular Weight: 28 and 75 kDa

Gene ID: 4000

OMIM: 115200

UniProt: P02545

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus