GNPTG antibody (C-Term)

Catalog No. ABIN1536973

This Rabbit Polyclonal antibody specifically detects GNPTG in WB. It exhibits reactivity toward Human.

Quick Overview for GNPTG antibody (C-Term) (ABIN1536973)

Target: GNPTG (N-Acetylglucosamine-1-Phosphate Transferase, gamma Subunit (GNPTG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPTG antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37561

Product Details anti-GNPTG Antibody

Binding Specificity: AA 266-296, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GNPTG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-296 amino acids from the C-terminal region of human GNPTG.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GNPTG Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for GNPTG

Target: GNPTG (N-Acetylglucosamine-1-Phosphate Transferase, gamma Subunit (GNPTG))

Alternative Name: GNPTG

Background: This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.

Molecular Weight: 33974

Gene ID: 84572

NCBI Accession: NP_115909

UniProt: Q9UJJ9