GPR39 antibody (C-Term)

Catalog No. ABIN1537229

The Rabbit Polyclonal anti-GPR39 antibody has been validated for WB. It is suitable to detect GPR39 in samples from Human. There is 1 publication available.

Quick Overview for GPR39 antibody (C-Term) (ABIN1537229)

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR39 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40394

Product Details anti-GPR39 Antibody

Binding Specificity: AA 379-407, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GPR39 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-GPR39 antibody (ABIN1537229)

Kolodziejski, Pruszynska-Oszmalek, Sassek, Kaczmarek, Szczepankiewicz, Billert, Mackowiak, Strowski, Nowak: "Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes." in: Journal of diabetes, Vol. 9, Issue 4, pp. 353-361, (2017) (PubMed).

Target Details for GPR39

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Alternative Name: GPR39

Background: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

Molecular Weight: 51329

Gene ID: 2863

NCBI Accession: NP_001499

UniProt: O43194

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour