NKX3-1 antibody (AA 58-86)

Catalog No. ABIN1538513

The Rabbit Polyclonal anti-NKX3-1 antibody is suitable to detect NKX3-1 in samples from Mouse. It has been validated for WB.

Quick Overview for NKX3-1 antibody (AA 58-86) (ABIN1538513)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40187

Product Details anti-NKX3-1 Antibody

Binding Specificity: AA 58-86

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Nkx3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of mouse Nkx3-1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Nkx3-1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: Nkx3-1

Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.

Molecular Weight: 26824

Gene ID: 18095

NCBI Accession: NP_035051

UniProt: P97436

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus