TAPBP antibody (N-Term)

Catalog No. ABIN1539369

The Rabbit Polyclonal anti-TAPBP antibody (Clone RB39546) (ABIN1539369) specifically detects TAPBP in WB. The antibody is reactive with Human samples.

Quick Overview for TAPBP antibody (N-Term) (ABIN1539369)

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAPBP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39546

Product Details anti-TAPBP Antibody

Binding Specificity: AA 42-70, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TAPBP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TAPBP Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TAPBP

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Alternative Name: TAPBP

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Molecular Weight: 47626

Gene ID: 6892

NCBI Accession: NP_003181, NP_757345, NP_757346

UniProt: O15533