ITPRIPL1 antibody (N-Term)

Catalog No. ABIN1539378

Product Details anti-ITPRIPL1 Antibody

Target: ITPRIPL1 (Inositol 1,4,5-Triphosphate Receptor Interacting Protein-Like 1 (ITPRIPL1))

Binding Specificity: AA 43-71, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPRIPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITPRIPL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human ITPRIPL1.

Clone: RB35892

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ITPRIPL1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for ITPRIPL1

Target: ITPRIPL1 (Inositol 1,4,5-Triphosphate Receptor Interacting Protein-Like 1 (ITPRIPL1))

Alternative Name: ITPRIPL1 (ITPRIPL1 Products)

Synonyms: 1700041B20Rik antibody, KIAA1754L antibody, inositol 1,4,5-triphosphate receptor interacting protein-like 1 antibody, ITPRIP like 1 antibody, inositol 1,4,5-trisphosphate receptor interacting protein-like 1 antibody, Itpripl1 antibody, ITPRIPL1 antibody

Background: ITPRIPL1 (inositol 1,4,5-triphosphate receptor-interacting protein-like 1), also known as KIAA1754L, is a 555 amino acid protein belonging to the ITPRIP family. ITPRIPL1 is a single-pass type I membrane protein expressed as two isoforms produced by alternative splicing events. The gene that encodes ITPRIPL1 maps to human chromosome 2, the second largest human chromosome, consisting of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr?m syndrome is due to mutations in the ALMS1 gene. It has been hypothesized that human chromosome 2 is the result of an ancient fusion of two ancestral chromosome due to its composition of a vestigial second centromere and vestigial telomeres.

Molecular Weight: 63395

Gene ID: 150771

NCBI Accession: NP_001008949, NP_848590

UniProt: Q6GPH6