Progesterone Receptor antibody (AA 349-377)

Catalog No. ABIN1539814

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB. It exhibits reactivity toward Human.

Quick Overview for Progesterone Receptor antibody (AA 349-377) (ABIN1539814)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 312CT8-2-1-6

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 349-377

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This PGR/PR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from human PGR/PR.

Isotype: IgM

Application Details

Application Notes: WB: 1:100~3200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: PGR/PR Antibody (Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

Molecular Weight: 98981

Gene ID: 5241

NCBI Accession: NP_000917, NP_001189403, NP_001258091

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration