Cathepsin K antibody

Catalog No. ABIN155107

This Rabbit Polyclonal antibody specifically detects Cathepsin K in WB, IP and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Cathepsin K antibody (ABIN155107)

Target: Cathepsin K (CTSK)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cathepsin K Antibody

Specificity: This antibody detects Cathepsin K at 43 kDa.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide surrounding amino acid 321 of rat cathepsin K.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mLImmunoprecipitationImmunohistochemistry on Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA as stabilizer and 0.01 % Thimerosal as preservative

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: Cathepsin K

Background: Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin K expression is highest in bone, cartilage, and skeletal muscle.Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Gene ID: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades