The Mouse Monoclonal anti-NEFM antibody (Clone 3H11) (ABIN1580448) specifically detects NEFM in WB, IHC, IF and ICC.
The antibody is reactive with Mammalian and Avian samples.
The antibody is supplied as 100 microliters of ascites fluid. The antibody works at a dilution of 1:500 for immunofluorescence microscopy and 1:5,000 for immunoblots.
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 4°C short term or -20°C long term.
Target
NEFM
(Neurofilament Triplet M Protein (NEFM))
Alternative Name
Neurofilament NF-M
Background
Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize of neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.