TIE1 antibody
Quick Overview for TIE1 antibody (ABIN1589940)
Target
See all TIE1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit Anti-Mouse TIE-1 Polyclonal Antibody
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Specificity
- Recombinant mouse sTIE-1
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Characteristics
- Chromosomal location: 4 D2.1, 4 50.0 cM
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Purification
- Protein A purified
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Immunogen
- Recombinant mouse sTIE-1 ( (ABIN1589959)
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Isotype
- IgG
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Application Notes
- Western Blot: use at 2-5 μg/mL.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS
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Handling Advice
- Centrifuge vial prior to opening.
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Storage
- 4 °C,-20 °C
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Storage Comment
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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Expiry Date
- 24 months
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Alternative Name
- TIE-1
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Background
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Synonyms: Tie1, TIE, tie-1, D430008P04Rik
Description: TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.
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Gene ID
- 21846
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NCBI Accession
- NM_011587, NP_035717
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UniProt
- Q06806
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Pathways
- RTK Signaling
Target
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