ADGRE5 (AA 240-435) antibody

Catalog No. ABIN1679103

Product Details

Target: ADGRE5

Binding Specificity: AA 240-435

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: NLEDIMRILA KSLPKGPFTY ISPSNTELTL MIQERGDKNV TMGQSSARMK LNWAVAAGAE DPGPAVAGIL SIQNMTTLLA NASLNLHSKK QAELEEIYES SIRGVQLRRL SAVNSIFLSH NNTKELNSPI LFAFSHLESS DGEAGRDPPA KDVMPGPRQE LLCAFWKSDS DRGGHWATEG CQVLGSKNGS TTCQCS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: ADGRE5

Synonyms: TM7LN1 antibody, adhesion G protein-coupled receptor E5 antibody, ADGRE5 antibody

Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.,ADGRE5,CD97,TM7LN1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,ADGRE5

Molecular Weight: 81 kDa/86 kDa/91 kDa

Gene ID: 976

UniProt: P48960