FOXO4 antibody (AA 346-505)

Catalog No. ABIN1679902

This Rabbit Polyclonal antibody specifically detects FOXO4 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for FOXO4 antibody (AA 346-505) (ABIN1679902)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-FOXO4 Antibody

Binding Specificity: AA 346-505

Sequence: FSPAEGPLSA GEGCFSSSQA LEALLTSDTP PPPADVLMTQ VDPILSQAPT LLLLGGLPSS SKLATGVGLC PKPLEAPGPS SLVPTLSMIA PPPVMASAPI PKALGTPVLT PPTEAASQDR MPQDLDLDMY MENLECDMDN IISDLMDEGE GLDFNFEPDP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 346-505 of human FOXO4 (NP_005929.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Alternative Name: FOXO4

Background: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.,AFX,AFX1,MLLT7,FOXO4,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,FOXO4

Molecular Weight: 47 kDa/53 kDa

Gene ID: 4303

UniProt: P98177

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation