TGFBI antibody (AA 481-683)
Quick Overview for TGFBI antibody (AA 481-683) (ABIN3023373)
Target
See all TGFBI AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 481-683
-
Sequence
- AHDKRGRYGT LFTMDRVLTP PMGTVMDVLK GDNRFSMLVA AIQSAGLTET LNREGVYTVF APTNEAFRAL PPRERSRLLG DAKELANILK YHIGDEILVS GGIGALVRLK SLQGDKLEVS LKNNVVSVNK EPVAEPDIMA TNGVVHVITN VLQPPANRPQ ERGDELADSA LEIFKQASAF SRASQRSVRL APVYQKLLER MKH
-
Cross-Reactivity
- Human, Mouse, Rat
-
Characteristics
- Polyclonal Antibodies
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 481-683 of human TGF beta induced TGF beta induced TGFBI (NP_000349.1).
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling." in: Scientific reports, Vol. 7, Issue 1, pp. 13321, (2017) (PubMed).
-
-
- TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))
-
Alternative Name
- TGFBI
-
Background
- This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.,TGFBI,BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Bone,Growth factor,Neuroscience,TGFBI
-
Molecular Weight
- 74 kDa
-
Gene ID
- 7045
-
UniProt
- Q15582
Target
-