C2ORF16 antibody (AA 1901-1984) (Alexa Fluor 350)

Catalog No. ABIN1692636

Product Details anti-C2ORF16 Antibody (Alexa Fluor 350)

Target: C2ORF16 (Chromosome 2 Open Reading Frame 16 (C2ORF16))

Binding Specificity: AA 1901-1984

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2ORF16 antibody is conjugated to Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf16

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C2ORF16

Target: C2ORF16 (Chromosome 2 Open Reading Frame 16 (C2ORF16))

Alternative Name: C2orf16 (C2ORF16 Products)

Synonyms: chromosome 2 open reading frame 16 antibody, C2orf16 antibody

Background:

Synonyms: Uncharacterized protein C2orf16, C2orf16

Background: C2orf16 (chromosome 2 open reading frame 16), also known as DKFZp434G118 or DKFZp781D2023, is a 1,984 amino acid protein encoded by a gene that maps to human chromosome 2p23.3. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Gene ID: 84226

UniProt: Q68DN1