c-FOS antibody (pSer374) (Alexa Fluor 350)

Catalog No. ABIN1692847

Product Details anti-c-FOS Antibody (Alexa Fluor 350)

Target: c-FOS (c-Fos) (c-Fos)

Binding Specificity: pSer374

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-FOS antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser374

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: c-Fos (c-Fos Products)

Synonyms: AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody

Background:

Synonyms: c-Fos phospho S374, c-Fos Ser374, c-Fos phospho Ser374, p-c-Fos Ser374, Cellular oncogene fos, FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus, FOS, FOS protein, G0 G1 switch regulatory protein 7, G0S7, Oncogene FOS, Proto oncogene protein c fos, v fos FBJ murine osteosarcoma viral oncogene homolog, FOS, AP-1, C-FOS, p55, FOS_HUMAN, Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7.

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].

Gene ID: 2353

Pathways: S100 Proteins