MKLN1 antibody (AA 301-400) (Alexa Fluor 350)

Catalog No. ABIN1693093

Product Details anti-MKLN1 Antibody (Alexa Fluor 350)

Target: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKLN1 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MKLN1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MKLN1

Target: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Alternative Name: MKLN1 (MKLN1 Products)

Synonyms: fc60a07 antibody, wu:fc60a07 antibody, mkln1 antibody, MGC81665 antibody, MKLN1 antibody, MGC139211 antibody, TWA2 antibody, A130067F06Rik antibody, AU015903 antibody, BB154892 antibody, Muskelin antibody, DKFZp468G1027 antibody, muskelin 1, intracellular mediator containing kelch motifs antibody, muskelin 1 antibody, muskelin 1 L homeolog antibody, mkln1 antibody, MKLN1 antibody, mkln1.L antibody, Mkln1 antibody

Background:

Synonyms: MKLN 1, Mkln1, MKLN1_HUMAN, muskelin 1, intracellular mediator containing kelch mots, Muskelin.

Background: Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98 % amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively.