GSTZ1 antibody (AA 11-110) (Alexa Fluor 488)

Catalog No. ABIN1694863

Product Details anti-GSTZ1 Antibody (Alexa Fluor 488)

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Binding Specificity: AA 11-110

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTZ1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glutathione Transferase zeta 1/MAAI

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GSTZ1

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Alternative Name: Glutathione Transferase zeta 1/MAAI (GSTZ1 Products)

Synonyms: GSTZ1-1 antibody, MAAI antibody, MAI antibody, zgc:113898 antibody, zgc:92869 antibody, PSPTO3554 antibody, DDBDRAFT_0204466 antibody, DDBDRAFT_0231608 antibody, DDB_0204466 antibody, DDB_0231608 antibody, CG9362 antibody, Dmel\CG9362 antibody, gstz1 antibody, glutathione S-transferase zeta 1 antibody, glutathione transferase zeta 1 (maleylacetoacetate isomerase) antibody, maleylacetoacetate isomerase antibody, Glutathione S transferase Z1 antibody, glutathione S-transferase zeta 1 L homeolog antibody, GSTZ1 antibody, Gstz1 antibody, gstz1 antibody, maiA antibody, hmgC antibody, Patl_1448 antibody, Pnap_2807 antibody, Bind_0562 antibody, Bphyt_0577 antibody, Dtpsy_1678 antibody, Hbal_2638 antibody, mai antibody, BC1002_0299 antibody, Fbal_2576 antibody, Mesop_3937 antibody, GstZ1 antibody, gstz1.L antibody

Background:

Synonyms: EC 2.5.1.18, EC 5.2.1.2, Glutathione S transferase zeta 1, GSTZ1-1, MAAI, MAAI_HUMAN.

Background: GSTZ1 is a member of the glutathione S transferase (GSTs) super family, encoding multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Several transcript variants of this gene encode multiple protein isoforms. GSTZ1 shows minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. It has low glutathione peroxidase activity with T butyl and cumene hydroperoxides and is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. Highest expression in liver followed by kidney, skeletal muscle and brain. Also expressed in melanocytes, synovium, placenta, breast and fetal liver and heart.